Coadministration of pexidartinib (a CYP3A4 inducer) with sensitive CYP3A substrates may result in severe therapeutic failures. If concomitant use is unavoidable, boost the CYP3A substrate dosage in accordance with authorized solution labeling.
cyclosporine will raise the level or impact of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
miconazole vaginal will improve the stage or impact of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Connect with your Health care company or go to the closest hospital emergency room immediately if you have any of such symptoms.
fluvoxamine will enhance the stage or result of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Before you choose HALCION, inform your healthcare supplier about all your clinical situations, such as should you:
Observational studies have shown that concomitant use of opioid analgesics and benzodiazepines raises the possibility of drug-linked mortality as compared to use of opioids by yourself. If a decision is made to prescribe Halcion concomitantly with opioids, prescribe the lowest powerful dosages and least durations of concomitant use, and follow sufferers intently for indications and indicators of respiratory despair and sedation.
Knowledge from in vitro research of triazolam counsel a doable drug interaction with triazolam for the next: sertraline and paroxetine. Knowledge from in vitro reports of benzodiazepines aside from triazolam advise a probable drug conversation with triazolam for the following: ergotamine, cyclosporine, amiodarone, nicardipine, and nifedipine.
chloramphenicol will improve the amount or influence of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
lorlatinib will lessen the level or impact of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or click here Use Alternate Drug. Avoid use of lorlatinib with CYP3A substrates, the place nominal focus improvements may produce significant therapeutic failures from the substrate.
The dose of this medicine are going to be distinct for various individuals. Follow your physician's orders or even the Instructions around the label. The following details incorporates only the normal doses of the drugs. In the event your dose differs, don't modify it Except your health care provider tells you to do so.
bosentan will reduce the level or result of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
There exists a pregnancy registry for Ladies who take HALCION through pregnancy. The purpose of the registry is to collect specifics of the wellness of you and your toddler.
Don't quit applying Halcion devoid of asking your medical professional. You will have daily life-threatening withdrawal signs when you halt using the medicine suddenly after prolonged-phrase use. Some withdrawal indicators may final as many as twelve months or for a longer time.